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MOSR and NDHA Genes Comprising G-Quadruplex as Promising Therapeutic Targets against Mycobacterium tuberculosis: Molecular Recognition by Mitoxantrone Suppresses Replication and Gene Regulation

Occurrence of non-canonical G-quadruplex (G4) DNA structures in the genome have been recognized as key factors in gene regulation and several other cellular processes. The mosR and ndhA genes involved in pathways of oxidation sensing regulation and ATP generation, respectively, make Mycobacterium tu...

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Detalles Bibliográficos
Autores principales: Dey, Arpita, Anand, Kushi, Singh, Amit, Prasad, Ramasare, Barthwal, Ritu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10217741/
https://www.ncbi.nlm.nih.gov/pubmed/37239338
http://dx.doi.org/10.3390/genes14050978