PCSK3 Overexpression in Sjögren’s Syndrome Patients May Be Regulated by rs4932178 SNP in Its Promoter Region and Correlates with IFN-γ Gene Expression

Background: The PCSK3 gene encodes for the protease enzyme Furin, which promotes proteolytic maturation of important regulators of the immune response, and also enhances the secretion of interferon-γ (IFN). Several studies have suggested its possible involvement in the pathogenesis of chronic inflam...

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Detalles Bibliográficos
Autores principales: Latini, Andrea, De Benedittis, Giada, Colafrancesco, Serena, Perricone, Carlo, Novelli, Giuseppe, Novelli, Lucia, Priori, Roberta, Ciccacci, Cinzia, Borgiani, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10217834/
https://www.ncbi.nlm.nih.gov/pubmed/37239341
http://dx.doi.org/10.3390/genes14050981

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10217834/
https://www.ncbi.nlm.nih.gov/pubmed/37239341
http://dx.doi.org/10.3390/genes14050981

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