Development of Procathepsin L (pCTS-L)-Inhibiting Lanosterol-Carrying Liposome Nanoparticles to Treat Lethal Sepsis

The pathogenesis of microbial infections and sepsis is partly attributable to dysregulated innate immune responses propagated by late-acting proinflammatory mediators such as procathepsin L (pCTS-L). It was previously not known whether any natural product could inhibit pCTS-L-mediated inflammation o...

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Detalles Bibliográficos
Autores principales: Chen, Weiqiang, Zhu, Cassie Shu, Qiang, Xiaoling, Chen, Shujin, Li, Jianhua, Wang, Ping, Tracey, Kevin J., Wang, Haichao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10217857/
https://www.ncbi.nlm.nih.gov/pubmed/37239992
http://dx.doi.org/10.3390/ijms24108649

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10217857/
https://www.ncbi.nlm.nih.gov/pubmed/37239992
http://dx.doi.org/10.3390/ijms24108649

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