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Cellular Protein Aggregates: Formation, Biological Effects, and Ways of Elimination

The accumulation of protein aggregates is the hallmark of many neurodegenerative diseases. The dysregulation of protein homeostasis (or proteostasis) caused by acute proteotoxic stresses or chronic expression of mutant proteins can lead to protein aggregation. Protein aggregates can interfere with a...

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Detalles Bibliográficos
Autores principales: Wen, Jun-Hao, He, Xiang-Hong, Feng, Ze-Sen, Li, Dong-Yi, Tang, Ji-Xin, Liu, Hua-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10217863/
https://www.ncbi.nlm.nih.gov/pubmed/37239937
http://dx.doi.org/10.3390/ijms24108593