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Electron-Induced Decomposition of 5-Bromo-4-thiouracil and 5-Bromo-4-thio-2′-deoxyuridine: The Effect of the Deoxyribose Moiety on Dissociative Electron Attachment

When modified uridine derivatives are incorporated into DNA, radical species may form that cause DNA damage. This category of molecules has been proposed as radiosensitizers and is currently being researched. Here, we study electron attachment to 5-bromo-4-thiouracil (BrSU), a uracil derivative, and...

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Detalles Bibliográficos
Autores principales: Izadi, Farhad, Szczyrba, Adrian, Datta, Magdalena, Ciupak, Olga, Demkowicz, Sebastian, Rak, Janusz, Denifl, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10217871/
https://www.ncbi.nlm.nih.gov/pubmed/37240053
http://dx.doi.org/10.3390/ijms24108706