Neuroprotection of Andrographolide against Neurotoxin MPP(+)-Induced Apoptosis in SH-SY5Y Cells via Activating Mitophagy, Autophagy, and Antioxidant Activities

Parkinson’s disease (PD) is associated with dopaminergic neuron loss and alpha-synuclein aggregation caused by ROS overproduction, leading to mitochondrial dysfunction and autophagy impairment. Recently, andrographolide (Andro) has been extensively studied for various pharmacological properties, suc...

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Detalles Bibliográficos
Autores principales: Prasertsuksri, Prachayaporn, Kraokaew, Pichnaree, Pranweerapaiboon, Kanta, Sobhon, Prasert, Chaithirayanon, Kulathida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10217882/
https://www.ncbi.nlm.nih.gov/pubmed/37239873
http://dx.doi.org/10.3390/ijms24108528

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10217882/
https://www.ncbi.nlm.nih.gov/pubmed/37239873
http://dx.doi.org/10.3390/ijms24108528

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