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Neuroprotection of Andrographolide against Neurotoxin MPP(+)-Induced Apoptosis in SH-SY5Y Cells via Activating Mitophagy, Autophagy, and Antioxidant Activities
Parkinson’s disease (PD) is associated with dopaminergic neuron loss and alpha-synuclein aggregation caused by ROS overproduction, leading to mitochondrial dysfunction and autophagy impairment. Recently, andrographolide (Andro) has been extensively studied for various pharmacological properties, suc...
Autores principales: | Prasertsuksri, Prachayaporn, Kraokaew, Pichnaree, Pranweerapaiboon, Kanta, Sobhon, Prasert, Chaithirayanon, Kulathida |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10217882/ https://www.ncbi.nlm.nih.gov/pubmed/37239873 http://dx.doi.org/10.3390/ijms24108528 |
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