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Dysfunctional Autophagy, Proteostasis, and Mitochondria as a Prelude to Age-Related Macular Degeneration

Retinal pigment epithelial (RPE) cell dysfunction is a key driving force of AMD. RPE cells form a metabolic interface between photoreceptors and choriocapillaris, performing essential functions for retinal homeostasis. Through their multiple functions, RPE cells are constantly exposed to oxidative s...

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Detalles Bibliográficos
Autores principales: Lenin, Raji Rajesh, Koh, Yi Hui, Zhang, Zheting, Yeo, Yan Zhuang, Parikh, Bhav Harshad, Seah, Ivan, Wong, Wendy, Su, Xinyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10217992/
https://www.ncbi.nlm.nih.gov/pubmed/37240109
http://dx.doi.org/10.3390/ijms24108763