Potential Clinically Relevant Effects of Sialylation on Human Serum AAG-Drug Interactions Assessed by Isothermal Titration Calorimetry: Insight into Pharmacoglycomics?

Human serum alpha-1 acid glycoprotein is an acute-phase plasma protein involved in the binding and transport of many drugs, especially basic and lipophilic substances. It has been reported that the sialic acid groups that terminate the N–glycan chains of alpha-1 acid glycoprotein change in response...

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Detalles Bibliográficos
Autores principales: Kerep, Robert, Šeba, Tino, Borko, Valentina, Weitner, Tin, Keser, Toma, Lauc, Gordan, Gabričević, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218007/
https://www.ncbi.nlm.nih.gov/pubmed/37239819
http://dx.doi.org/10.3390/ijms24108472

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218007/
https://www.ncbi.nlm.nih.gov/pubmed/37239819
http://dx.doi.org/10.3390/ijms24108472

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