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An Elusive Target: Inhibitors of JC Polyomavirus Infection and Their Development as Therapeutics for the Treatment of Progressive Multifocal Leukoencephalopathy

Progressive multifocal leukoencephalopathy (PML) is a rare demyelinating disease caused by infection with JC Polyomavirus (JCPyV). Despite the identification of the disease and isolation of the causative pathogen over fifty years ago, no antiviral treatments or prophylactic vaccines exist. Disease o...

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Detalles Bibliográficos
Autores principales: Kaiserman, Jacob, O’Hara, Bethany A., Haley, Sheila A., Atwood, Walter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218015/
https://www.ncbi.nlm.nih.gov/pubmed/37239927
http://dx.doi.org/10.3390/ijms24108580