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TGF-β Type I Receptor Signaling in Melanoma Liver Metastases Increases Metastatic Outgrowth

SIMPLE SUMMARY: Melanoma patients with liver metastasis have a poor prognosis, despite progress in therapeutic strategies. The cytokine Transforming Growth Factor β (TGF-β) plays a role in melanoma cells and acts on cells in the liver. We hypothesized that this cytokine influences the metastatic out...

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Detalles Bibliográficos
Autores principales: Marvin, Dieuwke L., Dijkstra, Jelmer, Zulfiqar, Rabia M., Vermeulen, Michiel, ten Dijke, Peter, Ritsma, Laila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218053/
https://www.ncbi.nlm.nih.gov/pubmed/37240029
http://dx.doi.org/10.3390/ijms24108676