Lipocalin-2 Deficiency Diminishes Canonical NLRP3 Inflammasome Formation and IL-1β Production in the Subacute Phase of Spinal Cord Injury

Spinal cord injury (SCI) results in the production of proinflammatory cytokines due to inflammasome activation. Lipocalin 2 (LCN2) is a small secretory glycoprotein upregulated by toll-like receptor (TLR) signaling in various cells and tissues. LCN2 secretion is induced by infection, injury, and met...

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Detalles Bibliográficos
Autores principales: Müller, Nina, Scheld, Miriam, Voelz, Clara, Gasterich, Natalie, Zhao, Weiyi, Behrens, Victoria, Weiskirchen, Ralf, Baazm, Maryam, Clarner, Tim, Beyer, Cordian, Sanadgol, Nima, Zendedel, Adib
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218144/
https://www.ncbi.nlm.nih.gov/pubmed/37240031
http://dx.doi.org/10.3390/ijms24108689

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218144/
https://www.ncbi.nlm.nih.gov/pubmed/37240031
http://dx.doi.org/10.3390/ijms24108689

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