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Lipocalin-2 Deficiency Diminishes Canonical NLRP3 Inflammasome Formation and IL-1β Production in the Subacute Phase of Spinal Cord Injury
Spinal cord injury (SCI) results in the production of proinflammatory cytokines due to inflammasome activation. Lipocalin 2 (LCN2) is a small secretory glycoprotein upregulated by toll-like receptor (TLR) signaling in various cells and tissues. LCN2 secretion is induced by infection, injury, and met...
Autores principales: | Müller, Nina, Scheld, Miriam, Voelz, Clara, Gasterich, Natalie, Zhao, Weiyi, Behrens, Victoria, Weiskirchen, Ralf, Baazm, Maryam, Clarner, Tim, Beyer, Cordian, Sanadgol, Nima, Zendedel, Adib |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218144/ https://www.ncbi.nlm.nih.gov/pubmed/37240031 http://dx.doi.org/10.3390/ijms24108689 |
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