Unveiling CD59-Antibody Interactions to Design Paratope-Mimicking Peptides for Complement Modulation

CD59 is an abundant immuno-regulatory human protein that protects cells from damage by inhibiting the complement system. CD59 inhibits the assembly of the Membrane Attack Complex (MAC), the bactericidal pore-forming toxin of the innate immune system. In addition, several pathogenic viruses, includin...

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Detalles Bibliográficos
Autores principales: Sandomenico, Annamaria, Ruggiero, Alessia, Iaccarino, Emanuela, Oliver, Angela, Squeglia, Flavia, Moreira, Miguel, Esposito, Luciana, Ruvo, Menotti, Berisio, Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218266/
https://www.ncbi.nlm.nih.gov/pubmed/37239905
http://dx.doi.org/10.3390/ijms24108561

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218266/
https://www.ncbi.nlm.nih.gov/pubmed/37239905
http://dx.doi.org/10.3390/ijms24108561

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