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Unveiling CD59-Antibody Interactions to Design Paratope-Mimicking Peptides for Complement Modulation

CD59 is an abundant immuno-regulatory human protein that protects cells from damage by inhibiting the complement system. CD59 inhibits the assembly of the Membrane Attack Complex (MAC), the bactericidal pore-forming toxin of the innate immune system. In addition, several pathogenic viruses, includin...

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Detalles Bibliográficos
Autores principales:	Sandomenico, Annamaria, Ruggiero, Alessia, Iaccarino, Emanuela, Oliver, Angela, Squeglia, Flavia, Moreira, Miguel, Esposito, Luciana, Ruvo, Menotti, Berisio, Rita
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218266/ https://www.ncbi.nlm.nih.gov/pubmed/37239905 http://dx.doi.org/10.3390/ijms24108561

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