Embryonic Stem Cell-Derived Neurons as a Model System for Epigenome Maturation during Development

DNA methylation in neurons is directly linked to neuronal genome regulation and maturation. Unlike other tissues, vertebrate neurons accumulate high levels of atypical DNA methylation in the CH sequence context (mCH) during early postnatal brain development. Here, we investigate to what extent neuro...

Descripción completa

Detalles Bibliográficos
Autores principales: Martin, Sally, Poppe, Daniel, Olova, Nelly, O’Leary, Conor, Ivanova, Elena, Pflueger, Jahnvi, Dechka, Jennifer, Simmons, Rebecca K., Cooper, Helen M., Reik, Wolf, Lister, Ryan, Wolvetang, Ernst J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218269/
https://www.ncbi.nlm.nih.gov/pubmed/37239317
http://dx.doi.org/10.3390/genes14050957

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218269/
https://www.ncbi.nlm.nih.gov/pubmed/37239317
http://dx.doi.org/10.3390/genes14050957

Ejemplares similares