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UBASH3A Interacts with PTPN22 to Regulate IL2 Expression and Risk for Type 1 Diabetes

UBASH3A is a negative regulator of T cell activation and IL-2 production and plays key roles in autoimmunity. Although previous studies revealed the individual effects of UBASH3A on risk for type 1 diabetes (T1D; a common autoimmune disease), the relationship of UBASH3A with other T1D risk factors r...

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Detalles Bibliográficos
Autores principales: Newman, Jeremy R. B., Concannon, Patrick, Ge, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218450/
https://www.ncbi.nlm.nih.gov/pubmed/37240014
http://dx.doi.org/10.3390/ijms24108671