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Innovative Rocuronium Bromide Topical Formulation for Targeted Skin Drug Delivery: Design, Comprehensive Characterization, In Vitro 2D/3D Human Cell Culture and Permeation

Cutaneous squamous cell carcinoma (cSCC) is the second-most common type of non-melanoma skin cancer and is linked to long-term exposure to ultraviolet (UV) radiation from the sun. Rocuronium bromide (RocBr) is an FDA-approved drug that targets p53-related protein kinase (PRPK) that inhibits the deve...

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Detalles Bibliográficos
Autores principales: Ruiz, Victor H., Encinas-Basurto, David, Sun, Bo, Eedara, Basanth Babu, Roh, Eunmiri, Alarcon, Neftali Ortega, Curiel-Lewandrowski, Clara, Bode, Ann M., Mansour, Heidi M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218466/
https://www.ncbi.nlm.nih.gov/pubmed/37240122
http://dx.doi.org/10.3390/ijms24108776