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NatB Catalytic Subunit Depletion Disrupts DNA Replication Initiation Leading to Senescence in MEFs

Alpha-aminoterminal acetyltransferase B (NatB) is a critical enzyme responsible for acetylating the aminoterminal end of proteins, thereby modifying approximately 21% of the proteome. This post-translational modification impacts protein folding, structure, stability, and interactions between protein...

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Detalles Bibliográficos
Autores principales: Elurbide, Jasmin, Carte, Beatriz, Guedes, Joana, Aldabe, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218504/
https://www.ncbi.nlm.nih.gov/pubmed/37240070
http://dx.doi.org/10.3390/ijms24108724