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NatB Catalytic Subunit Depletion Disrupts DNA Replication Initiation Leading to Senescence in MEFs
Alpha-aminoterminal acetyltransferase B (NatB) is a critical enzyme responsible for acetylating the aminoterminal end of proteins, thereby modifying approximately 21% of the proteome. This post-translational modification impacts protein folding, structure, stability, and interactions between protein...
Autores principales: | Elurbide, Jasmin, Carte, Beatriz, Guedes, Joana, Aldabe, Rafael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218504/ https://www.ncbi.nlm.nih.gov/pubmed/37240070 http://dx.doi.org/10.3390/ijms24108724 |
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