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EAE of Mice: Enzymatic Cross Site-Specific Hydrolysis of H2A Histone by IgGs against H2A, H1, H2B, H3, and H4 Histones and Myelin Basic Protein

Histones play vital roles in chromatin function and gene transcription; however, they are very harmful in the intercellular space because they stimulate systemic inflammatory and toxic responses. Myelin basic protein (MBP) is the major protein of the axon myelin–proteolipid sheath. Antibodies–abzyme...

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Detalles Bibliográficos
Autores principales: Urusov, Andrey E., Aulova, Kseniya S., Dmitrenok, Pavel S., Buneva, Valentina N., Nevinsky, Georgy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218518/
https://www.ncbi.nlm.nih.gov/pubmed/37239982
http://dx.doi.org/10.3390/ijms24108636