Pro-Osteogenic and Anti-Inflammatory Synergistic Effect of Orthosilicic Acid, Vitamin K2, Curcumin, Polydatin and Quercetin Combination in Young and Senescent Bone Marrow-Derived Mesenchymal Stromal Cells

During aging, bone marrow mesenchymal stromal cells (MSCs)—the precursors of osteoblasts—undergo cellular senescence, losing their osteogenic potential and acquiring a pro-inflammatory secretory phenotype. These dysfunctions cause bone loss and lead to osteoporosis. Prevention and intervention at an...

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Detalles Bibliográficos
Autores principales: Giordani, Chiara, Matacchione, Giulia, Giuliani, Angelica, Valli, Debora, Scarpa, Emanuele Salvatore, Antonelli, Antonella, Sabbatinelli, Jacopo, Giacchetti, Gilberta, Sabatelli, Sofia, Olivieri, Fabiola, Rippo, Maria Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218531/
https://www.ncbi.nlm.nih.gov/pubmed/37240169
http://dx.doi.org/10.3390/ijms24108820

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218531/
https://www.ncbi.nlm.nih.gov/pubmed/37240169
http://dx.doi.org/10.3390/ijms24108820

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