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Hepatocyte Nuclear Factor 4α (HNF4α) Plays a Controlling Role in Expression of the Retinoic Acid Receptor β (RARβ) Gene in Hepatocytes

HNF4α, a member of the nuclear receptor superfamily, regulates the genes involved in lipid and glucose metabolism. The expression of the RARβ gene in the liver of HNF4α knock-out mice was higher versus wildtype controls, whereas oppositely, RARβ promoter activity was 50% reduced by the overexpressio...

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Detalles Bibliográficos
Autores principales: Zolfaghari, Reza, Bonzo, Jessica A., Gonzalez, Frank J., Ross, A. Catharine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218549/
https://www.ncbi.nlm.nih.gov/pubmed/37239961
http://dx.doi.org/10.3390/ijms24108608