Cargando…
Hepatocyte Nuclear Factor 4α (HNF4α) Plays a Controlling Role in Expression of the Retinoic Acid Receptor β (RARβ) Gene in Hepatocytes
HNF4α, a member of the nuclear receptor superfamily, regulates the genes involved in lipid and glucose metabolism. The expression of the RARβ gene in the liver of HNF4α knock-out mice was higher versus wildtype controls, whereas oppositely, RARβ promoter activity was 50% reduced by the overexpressio...
Autores principales: | Zolfaghari, Reza, Bonzo, Jessica A., Gonzalez, Frank J., Ross, A. Catharine |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218549/ https://www.ncbi.nlm.nih.gov/pubmed/37239961 http://dx.doi.org/10.3390/ijms24108608 |
Ejemplares similares
-
The role of hepatocyte nuclear factor 4α (HNF4α) in tumorigenesis
por: Sang, Lei, et al.
Publicado: (2022) -
Crystallization of hepatocyte nuclear factor 4α (HNF4α) in complex with the HNF1α promoter element
por: Lu, Peng, et al.
Publicado: (2008) -
SUMOylation of HNF4α regulates protein stability and hepatocyte function
por: Zhou, Wenli, et al.
Publicado: (2012) -
SAT-162 Hepatocyte Nuclear Factor-4α (HNF44α) as a Target to Treat DM
por: Jorge dos Santos, Gustavo, et al.
Publicado: (2019) -
Proteomic Analysis of Native Hepatocyte Nuclear Factor-4α (HNF4α) Isoforms, Phosphorylation Status, and Interactive Cofactors
por: Daigo, Kenji, et al.
Publicado: (2011)