(E)-2-Benzylidenecyclanones: Part XVIII Study the Possible Link between Glutathione Reactivity and Cancer Cell Cytotoxic Effects of Some Cyclic Chalcone Analogs A Comparison of the Reactivity of the Open-Chain and the Seven-Membered Homologs

Non-enzymatic thiol addition into the α,β-unsaturated carbonyl system is associated with several biological effects. In vivo, the reactions can form small-molecule thiol (e.g., glutathione) or protein thiol adducts. The reaction of two synthetic (4′-methyl- and 4′-methoxy substituted) cyclic chalcon...

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Detalles Bibliográficos
Autores principales: Kenari, Fatemeh, Molnár, Szilárd, Borges, Igor D., Napolitano, Hamilton B., Perjési, Pál
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218606/
https://www.ncbi.nlm.nih.gov/pubmed/37239911
http://dx.doi.org/10.3390/ijms24108557

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218606/
https://www.ncbi.nlm.nih.gov/pubmed/37239911
http://dx.doi.org/10.3390/ijms24108557

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