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Study on the Effect of EZH2 Inhibitor Combined with TIGIT Monoclonal Antibody against Multiple Myeloma Cells

EZH2, a member of the polycomb repressive complex 2, induces trimethylation of the downstream gene at the histone three lysine 27 (H3K27me3) position to inhibit tumor cell proliferation. Here, we showed that the apoptosis rate and apoptotic protein expression increased after EZH2 inhibition, whereas...

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Detalles Bibliográficos
Autores principales: Liu, Zhaoyun, Jia, Yue, Yang, Chun, Liu, Hui, Shen, Hongli, Wang, Hao, Fu, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218613/
https://www.ncbi.nlm.nih.gov/pubmed/37239949
http://dx.doi.org/10.3390/ijms24108603