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Hepatic Pin1 Expression, Particularly in Nuclei, Is Increased in NASH Patients in Accordance with Evidence of the Role of Pin1 in Lipid Accumulation Shown in Hepatoma Cell Lines

Our previous studies using rodent models have suggested an essential role for Pin1 in the pathogenesis of non-alcoholic steatohepatitis (NASH). In addition, interestingly, serum Pin1 elevation has been reported in NASH patients. However, no studies have as yet examined the Pin1 expression level in h...

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Detalles Bibliográficos
Autores principales: Kanna, Machi, Nakatsu, Yusuke, Yamamotoya, Takeshi, Kushiyama, Akifumi, Fujishiro, Midori, Sakoda, Hideyuki, Ono, Hiraku, Arihiro, Koji, Asano, Tomoichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218692/
https://www.ncbi.nlm.nih.gov/pubmed/37240193
http://dx.doi.org/10.3390/ijms24108847