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A Theoretical Study of Organotin Binding in Aromatase

The widely used organotin compounds are notorious for their acute toxicity. Experiments revealed that organotin might cause reproductive toxicity by reversibly inhibiting animal aromatase functioning. However, the inhibition mechanism is obscure, especially at the molecular level. Compared to experi...

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Detalles Bibliográficos
Autores principales: Cheng, Shuming, Yang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218834/
https://www.ncbi.nlm.nih.gov/pubmed/37240300
http://dx.doi.org/10.3390/ijms24108954