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Encapsulation of Clofazimine by Cyclodextran: Preparation, Characterization, and In Vitro Release Properties

This study aimed to evaluate and compare the efficacy of cyclodextrans (CIs) and cyclodextrins (CDs) in improving the water solubility of a poorly water-soluble drug, clofazimine (CFZ). Among the evaluated CIs and CDs, CI-9 exhibited the highest percentage of drug inclusion and the highest solubilit...

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Detalles Bibliográficos
Autores principales: Hong, Seong-Jin, Kim, Young-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218955/
https://www.ncbi.nlm.nih.gov/pubmed/37240153
http://dx.doi.org/10.3390/ijms24108808