Complex Formation of an RNA Aptamer with a Part of HIV-1 Tat through Induction of Base Triples in Living Human Cells Proven by In-Cell NMR

An RNA aptamer that strongly binds to a target molecule has the potential to be a nucleic acid drug inside living human cells. To investigate and improve this potential, it is critical to elucidate the structure and interaction of RNA aptamers inside living cells. We examined an RNA aptamer for HIV-...

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Detalles Bibliográficos
Autores principales: Eladl, Omar, Yamaoki, Yudai, Kondo, Keiko, Nagata, Takashi, Katahira, Masato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218998/
https://www.ncbi.nlm.nih.gov/pubmed/37240414
http://dx.doi.org/10.3390/ijms24109069

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218998/
https://www.ncbi.nlm.nih.gov/pubmed/37240414
http://dx.doi.org/10.3390/ijms24109069

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