Extent of N-Terminus Folding of Semenogelin 1 Cleavage Product Determines Tendency to Amyloid Formation

It is known that four peptide fragments of predominant protein in human semen Semenogelin 1 (SEM1) (SEM1(86–107), SEM1(68–107), SEM1(49–107) and SEM1(45–107)) are involved in fertilization and amyloid formation processes. In this work, the structure and dynamic behavior of SEM1(45–107) and SEM1(49–1...

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Detalles Bibliográficos
Autores principales: Osetrina, Daria A., Kusova, Aleksandra M., Bikmullin, Aydar G., Klochkova, Evelina A., Yulmetov, Aydar R., Semenova, Evgenia A., Mukhametzyanov, Timur A., Usachev, Konstantin S., Klochkov, Vladimir V., Blokhin, Dmitriy S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219109/
https://www.ncbi.nlm.nih.gov/pubmed/37240295
http://dx.doi.org/10.3390/ijms24108949

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219109/
https://www.ncbi.nlm.nih.gov/pubmed/37240295
http://dx.doi.org/10.3390/ijms24108949

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