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αvβ3 Integrin as a Link between the Development of Fibrosis and Thyroid Hormones in Systemic Sclerosis

Systemic sclerosis (SSc) is an autoimmune disease characterized by fibrosis of the skin and internal organs. Key players mediating fibrosis are myofibroblasts (MF) that, following transforming growth factor β (TGFβ) exposure, produce a collagen-rich extracellular matrix (ECM) that induces myofibrobl...

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Detalles Bibliográficos
Autores principales: Kohon, Maia Yamila, Zaaroor Levy, Mor, Hornik-Lurie, Tzipi, Shalom, Avshalom, Berl, Ariel, Drucker, Liat, Levy, Yair, Tartakover Matalon, Shelly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219222/
https://www.ncbi.nlm.nih.gov/pubmed/37240272
http://dx.doi.org/10.3390/ijms24108927