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Modulation of Membrane Trafficking of AQP5 in the Lens in Response to Changes in Zonular Tension Is Mediated by the Mechanosensitive Channel TRPV1

In mice, the contraction of the ciliary muscle via the administration of pilocarpine reduces the zonular tension applied to the lens and activates the TRPV1-mediated arm of a dual feedback system that regulates the lens’ hydrostatic pressure gradient. In the rat lens, this pilocarpine-induced reduct...

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Detalles Bibliográficos
Autores principales: Petrova, Rosica S., Nair, Nikhil, Bavana, Nandini, Chen, Yadi, Schey, Kevin L., Donaldson, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219244/
https://www.ncbi.nlm.nih.gov/pubmed/37240426
http://dx.doi.org/10.3390/ijms24109080