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Engineering a Phosphoketolase Pathway to Supplement Cytosolic Acetyl-CoA in Aspergillus niger Enables a Significant Increase in Citric Acid Production

Citric acid is widely used in the food, chemical and pharmaceutical industries. Aspergillus niger is the workhorse used for citric acid production in industry. A canonical citrate biosynthesis that occurred in mitochondria was well established; however, some research suggested that the cytosolic cit...

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Detalles Bibliográficos
Autores principales: Liu, Jiao, Zhang, Shanshan, Li, Wenhao, Wang, Guanyi, Xie, Zhoujie, Cao, Wei, Gao, Weixia, Liu, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219267/
https://www.ncbi.nlm.nih.gov/pubmed/37233215
http://dx.doi.org/10.3390/jof9050504