Effect of Secretion Efficiency of Mutant KRAS Neoantigen by Lactococcus lactis on the Immune Response of a Mucosal Vaccine Delivery Vehicle Targeting Colorectal Cancer

Colorectal cancer (CRC) is often caused by mutations in the KRAS oncogene, making KRAS neoantigens a promising vaccine candidate for immunotherapy. Secreting KRAS antigens using live Generally Recognized as Safe (GRAS) vaccine delivery hosts such as Lactococcus lactis is deemed to be an effective st...

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Detalles Bibliográficos
Autores principales: Alias, Nur Aqlili Riana, Hoo, Winfrey Pui Yee, Siak, Pui Yan, Othman, Siti Sarah, Mohammed Alitheen, Noorjahan Banu, In, Lionel Lian Aun, Abdul Rahim, Raha, Song, Adelene Ai-Lian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219268/
https://www.ncbi.nlm.nih.gov/pubmed/37240273
http://dx.doi.org/10.3390/ijms24108928

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219268/
https://www.ncbi.nlm.nih.gov/pubmed/37240273
http://dx.doi.org/10.3390/ijms24108928

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