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Effect of Secretion Efficiency of Mutant KRAS Neoantigen by Lactococcus lactis on the Immune Response of a Mucosal Vaccine Delivery Vehicle Targeting Colorectal Cancer
Colorectal cancer (CRC) is often caused by mutations in the KRAS oncogene, making KRAS neoantigens a promising vaccine candidate for immunotherapy. Secreting KRAS antigens using live Generally Recognized as Safe (GRAS) vaccine delivery hosts such as Lactococcus lactis is deemed to be an effective st...
Autores principales: | Alias, Nur Aqlili Riana, Hoo, Winfrey Pui Yee, Siak, Pui Yan, Othman, Siti Sarah, Mohammed Alitheen, Noorjahan Banu, In, Lionel Lian Aun, Abdul Rahim, Raha, Song, Adelene Ai-Lian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219268/ https://www.ncbi.nlm.nih.gov/pubmed/37240273 http://dx.doi.org/10.3390/ijms24108928 |
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