Hfe Actions in Kupffer Cells Are Dispensable for Hepatic and Systemic Iron Metabolism

Mutations in the HFE/Hfe gene cause Hereditary Hemochromatosis (HH), a highly prevalent genetic disorder characterized by elevated iron deposition in multiple tissues. HFE acts in hepatocytes to control hepcidin expression, whereas HFE actions in myeloid cells are required for cell-autonomous and sy...

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Detalles Bibliográficos
Autores principales: Knoop, Paul, Yilmaz, Dilay, Paganoni, Rossana, Steele-Perkins, Peter, Gruber, Andreas, Akdogan, Banu, Zischka, Hans, Leopold, Kerstin, Vujić Spasić, Maja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219340/
https://www.ncbi.nlm.nih.gov/pubmed/37240294
http://dx.doi.org/10.3390/ijms24108948

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219340/
https://www.ncbi.nlm.nih.gov/pubmed/37240294
http://dx.doi.org/10.3390/ijms24108948

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