PPAR-Gamma Orchestrates EMT, AGE, and Cellular Senescence Pathways in Colonic Epithelium and Restrains the Progression of IBDs

Intestinal fibrosis, the most common complication of inflammatory bowel disease (IBD), is characterized by an uncontrolled deposition of extracellular matrix proteins leading to complications resolvable only with surgery. Transforming growth factor is the key player in the epithelial-mesenchymal tra...

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Detalles Bibliográficos
Autores principales: Pompili, Simona, Vetuschi, Antonella, Latella, Giovanni, Smakaj, Amarildo, Sferra, Roberta, Cappariello, Alfredo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219383/
https://www.ncbi.nlm.nih.gov/pubmed/37240299
http://dx.doi.org/10.3390/ijms24108952

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219383/
https://www.ncbi.nlm.nih.gov/pubmed/37240299
http://dx.doi.org/10.3390/ijms24108952

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