Cargando…

PPAR-Gamma Orchestrates EMT, AGE, and Cellular Senescence Pathways in Colonic Epithelium and Restrains the Progression of IBDs

Intestinal fibrosis, the most common complication of inflammatory bowel disease (IBD), is characterized by an uncontrolled deposition of extracellular matrix proteins leading to complications resolvable only with surgery. Transforming growth factor is the key player in the epithelial-mesenchymal tra...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pompili, Simona, Vetuschi, Antonella, Latella, Giovanni, Smakaj, Amarildo, Sferra, Roberta, Cappariello, Alfredo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219383/ https://www.ncbi.nlm.nih.gov/pubmed/37240299 http://dx.doi.org/10.3390/ijms24108952

Ejemplares similares

Ferroptosis resistance cooperates with cellular senescence in the overt stage of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis
por: Vetuschi, Antonella, et al.
Publicado: (2022)

Prolonged Chronic Consumption of a High Fat with Sucrose Diet Alters the Morphology of the Small Intestine
por: Sferra, Roberta, et al.
Publicado: (2021)

Extracellular Vesicles and Resistance to Anticancer Drugs: A Tumor Skeleton Key for Unhinging Chemotherapies
por: Pompili, Simona, et al.
Publicado: (2022)

The Charming World of the Extracellular Matrix: A Dynamic and Protective Network of the Intestinal Wall
por: Pompili, Simona, et al.
Publicado: (2021)

Localization of αυβ6 Integrin-TGF-β1/Smad3, mTOR and PPARγ in Experimental Colorectal Fibrosis
por: Latella, G., et al.
Publicado: (2013)

Role of glycogen synthase kinase-3β and PPAR-γ on epithelial-to-mesenchymal transition in DSS-induced colorectal fibrosis
por: Di Gregorio, Jacopo, et al.
Publicado: (2017)

Can Nrf2 Modulate the Development of Intestinal Fibrosis and Cancer in Inflammatory Bowel Disease?
por: Pompili, Simona, et al.
Publicado: (2019)

Interaction between sphingosine kinase/sphingosine 1 phosphate and transforming growth factor-β/Smads pathways in experimental intestinal fibrosis. An in vivo immunohistochemical study
por: Sferra, Roberta, et al.
Publicado: (2018)

Epidermal growth factor-like domain multiple 7 (EGFL7): Expression and possible effect on biliary epithelium growth in cholangiocarcinoma
por: Mammola, Caterina L., et al.
Publicado: (2018)

Is mastocytic colitis a specific clinical-pathological entity?
por: Vernia, Filippo, et al.
Publicado: (2022)

The Impact of PPARγ Genetic Variants on IBD Susceptibility and IBD Disease Course
por: Mwinyi, Jessica, et al.
Publicado: (2012)

PPARs-Orchestrated Metabolic Homeostasis in the Adipose Tissue
por: Sun, Chen, et al.
Publicado: (2021)

Neurovascular alterations of muscularis propria in the human anterior vaginal wall in pelvic organ prolapse
por: Sferra, R, et al.
Publicado: (2019)

Socs3 induction by PPARγ restrains cancer-promoting inflammation
por: Végran, Frédérique, et al.
Publicado: (2013)

Can the AGE/RAGE/ERK signalling pathway and the epithelial-to-mesenchymal transition interact in the pathogenesis of chronic rhinosinusitis with nasal polyps?
por: Vetuschi, Antonella, et al.
Publicado: (2020)

Primary Cilia Restrain PI3K-AKT Signaling to Orchestrate Human Decidualization
por: Li, Bo, et al.
Publicado: (2022)

Changes in Muscularis Propria of Anterior Vaginal Wall in Women with Pelvic Organ Prolapse
por: Vetuschi, A., et al.
Publicado: (2016)

PPARγ Acetylation Orchestrates Adipose Plasticity and Metabolic Rhythms
por: He, Ying, et al.
Publicado: (2022)

Development of hepatocellular cancer induced by long term low fat-high carbohydrate diet in a NAFLD/NASH mouse model
por: Tessitore, Alessandra, et al.
Publicado: (2017)

The possible prognostic role of histone deacetylase and transforming growth factor β/ Smad signaling in high grade gliomas treated by radio-chemotherapy: a preliminary immunohistochemical study
por: Sferra, Roberta, et al.
Publicado: (2017)

PPAR-δ senses and orchestrates clearance of apoptotic cells to promote tolerance
por: Mukundan, Lata, et al.
Publicado: (2009)

NIPSNAP1 directs dual mechanisms to restrain senescence in cancer cells
por: Gao, Enyi, et al.
Publicado: (2023)

Posterior Percutaneous Pedicle Screws Fixation Versus Open Surgical Instrumented Fusion for Thoraco-Lumbar Spinal Metastases Palliative Management: A Systematic Review and Meta-analysis
por: Perna, Andrea, et al.
Publicado: (2022)

Senescence-activated enhancer landscape orchestrates the senescence-associated secretory phenotype in murine fibroblasts
por: Guan, Yiting, et al.
Publicado: (2020)

Coming to “Grp(s)” with Senescence in the Alveolar Epithelium
por: Winters, Nichelle I., et al.
Publicado: (2020)

When Insult Is Added to Injury: Cross Talk between ILCs and Intestinal Epithelium in IBD
por: van der Gracht, Esmé, et al.
Publicado: (2016)

PPARγ agonists promote differentiation of cancer stem cells by restraining YAP transcriptional activity
por: Basu-Roy, Upal, et al.
Publicado: (2016)

Proteome Landscape of Epithelial-to-Mesenchymal Transition (EMT) of Retinal Pigment Epithelium Shares Commonalities With Malignancy-Associated EMT
por: Sripathi, Srinivasa R., et al.
Publicado: (2021)

PPAR Gamma and Hepatic Stellate Cells
por: Hazra, Saswati, et al.
Publicado: (2004)

The Role of PPAR Gamma in Systemic Sclerosis
por: Dantas, Andréa Tavares, et al.
Publicado: (2015)

PPAR Gamma and Viral Infections of the Brain
por: Layrolle, Pierre, et al.
Publicado: (2021)

PPAR-gamma Fun(gi) With Prostaglandin
por: Evans, Robert J., et al.
Publicado: (2020)

Newer generation straight humeral nails allow faster bone healing and better functional outcome at mid-term
por: Mocini, Fabrizio, et al.
Publicado: (2021)

Clinical Application of Adipose Derived Stem Cells for the Treatment of Aseptic Non-Unions: Current Stage and Future Perspectives—Systematic Review
por: Smakaj, Amarildo, et al.
Publicado: (2022)

Anterior intrapelvic approach and suprapectineal quadrilateral surface plate for acetabular fractures with anterior involvement: a retrospective study of 34 patients
por: Ciolli, Gianluca, et al.
Publicado: (2021)

Outcomes of acetabular fractures treated with acute fix and replace versus open reduction and internal fixation in elderly population: a multicentric retrospective study
por: Smakaj, Amarildo, et al.
Publicado: (2022)

Endometrial regeneration with endometrial epithelium: homologous orchestration with endometrial stroma as a feeder
por: Yokomizo, Ryo, et al.
Publicado: (2021)

Autophagy resists EMT process to maintain retinal pigment epithelium homeostasis
por: Feng, Hao, et al.
Publicado: (2019)

Orchestral works
por: Casella, Alfredo, 1883-1947
Publicado: (1994)

The role of the oncofetal H19 lncRNA in tumor metastasis: orchestrating the EMT-MET decision
por: Matouk, Imad J., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_f6il4rhad80p9g6rup271rf6fr