Nkx2-5 Loss of Function in the His-Purkinje System Hampers Its Maturation and Leads to Mechanical Dysfunction

The ventricular conduction or His-Purkinje system (VCS) mediates the rapid propagation and precise delivery of electrical activity essential for the synchronization of heartbeats. Mutations in the transcription factor Nkx2-5 have been implicated in a high prevalence of developing ventricular conduct...

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Detalles Bibliográficos
Autores principales: Choquet, Caroline, Sicard, Pierre, Vahdat, Juliette, Nguyen, Thi Hong Minh, Kober, Frank, Varlet, Isabelle, Bernard, Monique, Richard, Sylvain, Kelly, Robert G., Lalevée, Nathalie, Miquerol, Lucile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219388/
https://www.ncbi.nlm.nih.gov/pubmed/37233161
http://dx.doi.org/10.3390/jcdd10050194

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219388/
https://www.ncbi.nlm.nih.gov/pubmed/37233161
http://dx.doi.org/10.3390/jcdd10050194

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