Evaluation of a Novel FKS1 R1354H Mutation Associated with Caspofungin Resistance in Candida auris Using the CRISPR-Cas9 System

Outbreaks of invasive infections, with high mortality rates, caused by multidrug-resistant Candida auris have been reported worldwide. Although hotspot mutations in FKS1 are an established cause of echinocandin resistance, the actual contribution of these mutations to echinocandin resistance remains...

Descripción completa

Detalles Bibliográficos
Autores principales: Kiyohara, Maiko, Miyazaki, Taiga, Okamoto, Michiyo, Hirayama, Tatsuro, Makimura, Koichi, Chibana, Hiroji, Nakada, Nana, Ito, Yuya, Sumiyoshi, Makoto, Ashizawa, Nobuyuki, Takeda, Kazuaki, Iwanaga, Naoki, Takazono, Takahiro, Izumikawa, Koichi, Yanagihara, Katsunori, Kohno, Shigeru, Mukae, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219442/
https://www.ncbi.nlm.nih.gov/pubmed/37233240
http://dx.doi.org/10.3390/jof9050529

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219442/
https://www.ncbi.nlm.nih.gov/pubmed/37233240
http://dx.doi.org/10.3390/jof9050529

Ejemplares similares