Neurosteroids Mediate Neuroprotection in an In Vitro Model of Hypoxic/Hypoglycaemic Excitotoxicity via δ-GABA(A) Receptors without Affecting Synaptic Plasticity

Neurosteroids and benzodiazepines are modulators of the GABA(A) receptors, thereby causing anxiolysis. Furthermore, benzodiazepines such as midazolam are known to cause adverse side-effects on cognition upon administration. We previously found that midazolam at nanomolar concentrations (10 nM) block...

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Detalles Bibliográficos
Autores principales: Puig-Bosch, Xènia, Ballmann, Markus, Bieletzki, Stefan, Antkowiak, Bernd, Rudolph, Uwe, Zeilhofer, Hanns Ulrich, Rammes, Gerhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219454/
https://www.ncbi.nlm.nih.gov/pubmed/37240402
http://dx.doi.org/10.3390/ijms24109056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219454/
https://www.ncbi.nlm.nih.gov/pubmed/37240402
http://dx.doi.org/10.3390/ijms24109056

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