Hypoxia Is Associated with Increased Immune Infiltrates and Both Anti-Tumour and Immune Suppressive Signalling in Muscle-Invasive Bladder Cancer

Hypoxia and a suppressive tumour microenvironment (TME) are both independent negative prognostic factors for muscle-invasive bladder cancer (MIBC) that contribute to treatment resistance. Hypoxia has been shown to induce an immune suppressive TME by recruiting myeloid cells that inhibit anti-tumour...

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Detalles Bibliográficos
Autores principales: Smith, Vicky, Lee, Dave, Reardon, Mark, Shabbir, Rekaya, Sahoo, Sudhakar, Hoskin, Peter, Choudhury, Ananya, Illidge, Timothy, West, Catharine M. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219458/
https://www.ncbi.nlm.nih.gov/pubmed/37240301
http://dx.doi.org/10.3390/ijms24108956

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219458/
https://www.ncbi.nlm.nih.gov/pubmed/37240301
http://dx.doi.org/10.3390/ijms24108956

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