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Hypoxia Is Associated with Increased Immune Infiltrates and Both Anti-Tumour and Immune Suppressive Signalling in Muscle-Invasive Bladder Cancer
Hypoxia and a suppressive tumour microenvironment (TME) are both independent negative prognostic factors for muscle-invasive bladder cancer (MIBC) that contribute to treatment resistance. Hypoxia has been shown to induce an immune suppressive TME by recruiting myeloid cells that inhibit anti-tumour...
Autores principales: | Smith, Vicky, Lee, Dave, Reardon, Mark, Shabbir, Rekaya, Sahoo, Sudhakar, Hoskin, Peter, Choudhury, Ananya, Illidge, Timothy, West, Catharine M. L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219458/ https://www.ncbi.nlm.nih.gov/pubmed/37240301 http://dx.doi.org/10.3390/ijms24108956 |
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