Multi-Gene Next-Generation Sequencing Panel for Analysis of BRCA1/BRCA2 and Homologous Recombination Repair Genes Alterations Metastatic Castration-Resistant Prostate Cancer

Despite significant therapeutic advances, metastatic CRPC (mCRPC) remains a lethal disease. Mutations in homologous recombination repair (HRR) genes are frequent in mCRPC, and tumors harboring these mutations are known to be sensitive to PARP inhibitors. The aim of this study was to verify the techn...

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Detalles Bibliográficos
Autores principales: Maloberti, Thais, De Leo, Antonio, Coluccelli, Sara, Sanza, Viviana, Gruppioni, Elisa, Altimari, Annalisa, Zagnoni, Stefano, Giunchi, Francesca, Vasuri, Francesco, Fiorentino, Michelangelo, Mollica, Veronica, Ferrari, Simona, Miccoli, Sara, Visani, Michela, Turchetti, Daniela, Massari, Francesco, Tallini, Giovanni, de Biase, Dario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219522/
https://www.ncbi.nlm.nih.gov/pubmed/37240284
http://dx.doi.org/10.3390/ijms24108940

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219522/
https://www.ncbi.nlm.nih.gov/pubmed/37240284
http://dx.doi.org/10.3390/ijms24108940

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