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Multi-Gene Next-Generation Sequencing Panel for Analysis of BRCA1/BRCA2 and Homologous Recombination Repair Genes Alterations Metastatic Castration-Resistant Prostate Cancer
Despite significant therapeutic advances, metastatic CRPC (mCRPC) remains a lethal disease. Mutations in homologous recombination repair (HRR) genes are frequent in mCRPC, and tumors harboring these mutations are known to be sensitive to PARP inhibitors. The aim of this study was to verify the techn...
Autores principales: | Maloberti, Thais, De Leo, Antonio, Coluccelli, Sara, Sanza, Viviana, Gruppioni, Elisa, Altimari, Annalisa, Zagnoni, Stefano, Giunchi, Francesca, Vasuri, Francesco, Fiorentino, Michelangelo, Mollica, Veronica, Ferrari, Simona, Miccoli, Sara, Visani, Michela, Turchetti, Daniela, Massari, Francesco, Tallini, Giovanni, de Biase, Dario |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219522/ https://www.ncbi.nlm.nih.gov/pubmed/37240284 http://dx.doi.org/10.3390/ijms24108940 |
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