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Three Layers of Personalized Medicine in the Use of Sirolimus and Its Derivatives for the Treatment of Cancer

Rapamycin and its derivatives are mTOR inhibitors which are FDA-approved for use as immunosuppressants and chemotherapeutic agents. These agents are currently approved to treat renal cell carcinomas, soft tissue sarcomas, and other rare tumors. As tumor treatment paradigms are moving away from organ...

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Detalles Bibliográficos
Autores principales: Delgado, Andres, Enkemann, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219548/
https://www.ncbi.nlm.nih.gov/pubmed/37240915
http://dx.doi.org/10.3390/jpm13050745