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uORF4u: a tool for annotation of conserved upstream open reading frames

SUMMARY: Upstream open reading frames (uORFs, often encoding so-called leader peptides) can regulate translation and transcription of downstream main ORFs (mORFs) in prokaryotes and eukaryotes. However, annotation of novel functional uORFs is challenging due to their short size of usually <100 co...

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Detalles Bibliográficos
Autores principales: Egorov, Artyom A, Atkinson, Gemma C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219788/
https://www.ncbi.nlm.nih.gov/pubmed/37184890
http://dx.doi.org/10.1093/bioinformatics/btad323