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uORF4u: a tool for annotation of conserved upstream open reading frames
SUMMARY: Upstream open reading frames (uORFs, often encoding so-called leader peptides) can regulate translation and transcription of downstream main ORFs (mORFs) in prokaryotes and eukaryotes. However, annotation of novel functional uORFs is challenging due to their short size of usually <100 co...
Autores principales: | Egorov, Artyom A, Atkinson, Gemma C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219788/ https://www.ncbi.nlm.nih.gov/pubmed/37184890 http://dx.doi.org/10.1093/bioinformatics/btad323 |
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