Rapid Pacing Decreases L-type Ca(2+) Current and Alters Cacna1c Isogene Expression in Primary Cultured Rat Left Ventricular Myocytes

The L-type calcium current (I(CaL)) is the first step in cardiac excitation–contraction-coupling and plays an important role in regulating contractility, but also in electrical and mechanical remodeling. Primary culture of cardiomyocytes, a widely used tool in cardiac ion channel research, is associ...

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Detalles Bibliográficos
Autores principales: Ritzer, Anne, Roeschl, Tobias, Nay, Sandra, Rudakova, Elena, Volk, Tilmann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219890/
https://www.ncbi.nlm.nih.gov/pubmed/36995425
http://dx.doi.org/10.1007/s00232-023-00284-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219890/
https://www.ncbi.nlm.nih.gov/pubmed/36995425
http://dx.doi.org/10.1007/s00232-023-00284-y

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